Vortioxetine Hydrobromide Powder

Vortioxetine Hydrobromide Powder
Details
Product Name: Vortioxetine Hydrobromide Powder
Alternative Names: 1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine hydrobromide, vortioxetine research-grade raw solid
Specification: Purity ≥99.2%, Research Grade, HPLC quantified, custom purity options available
CAS No.: 960203-27-4
Appearance: Off-white to pale beige crystalline solid powder, sparingly soluble in water, freely soluble in dilute acidic aqueous solutions, stable under inert, dry and dark ambient storage conditions.
Core Advantages: Controlled low-temperature recrystallization to refine crystal morphology; strict trace heavy metal and residual solvent testing; consistent receptor-target bioactivity across production batches; complete impurity profiling and mass spectrum structural validation; compatible with neuronal cell culture media, suitable for in-vitro serotonin receptor pharmacological assays.
Service Support: Small lab trial batches in stock; light-protected ambient-temperature safe shipment for light-sensitive crystalline solids; customizable foil bag packing sizes; complete document package including COA and HPLC traces; dedicated technical consultation for preclinical neuroscience formulation teams.
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Product Details

Product Description

 

Vortioxetine Hydrobromide is a multi-modal serotonergic agent, designed for laboratory research on central nervous system neurotransmitter regulation. Its unique piperazine and aryl sulfide chemical backbone makes it widely adopted to prepare cell culture media for serotonin receptor-related in-vitro cell models. Researchers utilize this raw solid to investigate modulation of multiple serotonin receptor subtypes, construct in-vitro neuronal models related to mood disorder pathways, run compound photostability trials, and verify feasibility for solid oral pharmaceutical intermediate development.
When kept under sealed dry, low light room-temperature lab storage, this high-purity crystalline powder maintains stable dissolution performance after aqueous preparation. It retains consistent physicochemical properties in buffered test matrices, delivering reliable reference material for receptor binding assays and photodegradation studies. It is ideal for early-stage oral solid formulation screening and exploratory modification of small molecule neuroactive structures.

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COA

 

 

Items Specifications
Appearance White powder
Loss on Drying ≤2.0%
Residue on Ignition ≥0.5%
Lead ≤1 ppm
Arsenic ≤1 ppm
Cadmium ≤1 ppm
Mercury ≤0.1 ppm
Total Aerobic Count ≤1000 CFU/g
Yeast & Mold ≤100 CFU/g
E.Coli, Salmonella Negative
Shelf Life 24 months (sealed and stored away from light)

 

Functions and Effects

 

 

◆ In-vitro Assay for Serotonin Receptor Subtype Modulation
Acts as a pharmacological additive in cell incubation systems to evaluate the regulatory activity on multiple serotonin receptors during in-vitro neuropharmacology screening trials.


◆ Evaluation of Small Molecule Photolytic Degradation
Serves as certified reference material to track photodegradation byproduct formation under varied light intensity and pH conditions within cell-free buffered reaction matrices.


◆ Scaffold for Neuroactive Small Molecule Derivatization
Provides validated small-molecule structural backbone for synthetic chemistry lab work, enabling derivative synthesis and research on structure–activity relationships for multi-target CNS candidate compounds.


◆ Compatibility with Buffered Aqueous Cell Culture Media
Dissolves readily in dilute acidic aqueous buffers; can be blended with physiological salts to prepare multi-component working assay buffers for cellular neuroscience pharmacology work.

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Application Fields

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◆ Mechanism Research of In-vitro Serotonergic Neuropharmacology
Lab reference reagent for preparing cell culture working solutions for serotonin receptor screening, supporting iterative formulation screening workflows for neuropharmacology candidate discovery.


◆ Pre-formulation Research for Oral Solid Dosage Forms
Employed in bench-scale formulation development of tablets and capsules, acting as core active raw material to test novel delivery strategies for oral CNS-active compounds.


◆ Analytical Method Validation & Impurity Identification for Small Molecules
High-purity reference standard for impurity profiling, photostability comparison tests and benchmark solution validation for pharmaceutical raw material analysis.

Business Scope

 

 

0421001

 

Packaging And Transportation Methods

 

 

001

 

Certificationss

 

 

222

 

FAQ

 

 

Q1:What primary laboratory applications does Vortioxetine Hydrobromide Powder ≥99.2% serve?
A:It is mainly used for in-vitro serotonin multi-receptor research, photolytic stability testing of small molecules and early oral solid formulation exploration.
Q2:What is its CAS registration number?
A:CAS 960203-27-4.
 
Q3:Can we adjust packing quantity besides standard Research Grade ≥99.2%?
A:Yes, both net weight and purity grade can be adjusted to match your lab experimental design.
 
Q4:Can Vortioxetine Hydrobromide Powder be used directly for human clinical therapy?
A:This product is exclusively for laboratory research. It is not approved for human or animal clinical administration.
Q5:What storage recommendations apply to Vortioxetine Hydrobromide raw powder?
A:Store in sealed dry, light-shielded containers at ambient temperature. Exposure to strong light and high humidity must be avoided to prevent degradation and moisture uptake.
Q6:How does solubility vary between water and organic solvents?
A:Sparingly soluble in purified water; freely soluble in dilute acid aqueous solution; moderately soluble in polar aprotic solvents; poorly soluble in nonpolar organic solvents.
Q7:Will batch impurity variation interfere with my cellular receptor binding experiments?
A:Multi-step low-temperature recrystallization minimizes impurities; each batch comes with complete impurity test reports for your experiment risk assessment.
Q8:Are small trial quantities available for preliminary pharmacological screening?
A:Yes, we supply 100mg–1g trial packages for your initial in-vitro pharmacological testing.
 
How To Cooperate With Us?

Our address

No. 56, Jinye 1st Road, Hi-Tech Zone, Xi'an,Shaanxi   Province, China

Phone Number

18192393517

E-mail

dennis04@xaltbio.com

 

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