Latanoprost Powder

Latanoprost Powder
Details
Product Name: Latanoprost Powder
Alternative Names: Isopropyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate, prostaglandin F2α analogue lab raw material
Specification: HPLC ≥99.0%, research use only, custom assay specifications available upon request
CAS No.: 130209-82-4
Appearance: White powder. It demonstrates negligible solubility in aqueous medium while dissolving freely in DMSO, ethanol and chloroform. Photolysis will occur upon prolonged illumination. Stable under inert, anhydrous and dim ambient conditions.
Core Advantages: Low-temperature fractional purification protects the ester side chain from hydrolytic breakdown. Every batch undergoes heavy metal screening and residual solvent detection complying with pharmaceutical research standards. Inter-batch FP receptor bioactivity remains consistent. Full mass spectral identification and related-substance profiling are provided for each lot. It can be incorporated into cultured ocular tissue media to support prostaglandin receptor in-vitro pharmacological testing.
Service Support: Small lab-scale trial lots are held in stock. Special amber light-proof packaging is adopted for transit to prevent photodegradation of this light-sensitive powder compound. Multiple packing sizes can be tailored to client needs. Complete document set including COA and HPLC chromatograms is attached to shipments. Our technical team offers guidance on sample handling and ophthalmic formulation exploration for preclinical projects.
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Product Details

Product Description

 

Latanoprost functions as a selective FP prostaglandin receptor agonist for laboratory studies investigating aqueous humour outflow modulation within ocular tissue. Its characteristic cyclopentane heptenoate pharmacophore is widely adopted to prepare cell incubation medium for building in-vitro glaucoma-related ocular cell models. Researchers utilize this raw substance to examine FP receptor signalling cascades, establish trabecular meshwork cell models associated with intraocular pressure control, conduct photostability assessment trials, and assess the potential of this compound as an intermediate for novel ophthalmic solution development.
When sealed in anhydrous, dim-light storage at room temperature, this high-purity substance maintains stable physicochemical traits in ocular simulated buffer matrices, acting as reliable reference material for receptor binding assays and light-induced degradation research. It fits well for early-stage screening of ophthalmic liquid formulations and structural modification exploration of prostanoid analogues.

product-1281-1279

COA

 

 

Items Specifications
Appearance White powder
Loss on Drying ≤1.0%
Residue on Ignition ≥0.1%
Lead ≤2 ppm
Arsenic ≤1 ppm
Cadmium ≤1 ppm
Mercury ≤0.1 ppm
Total Aerobic Count ≤1000 CFU/g
Yeast & Mold ≤100 CFU/g
E.Coli, Salmonella Negative
Shelf Life 24 months (sealed and stored away from light)

 

Functions and Effects

 

 

• FP Receptor Activation Assay in Ocular Cell Culture

Serves as a test agent within cell incubation systems to quantify agonist potency targeting prostaglandin FP receptors during in-vitro ocular pharmacology screening campaigns.

• Photodegradation Kinetic Research 

Works as authenticated reference material to monitor the generation of light-triggered degradation byproducts under varied illumination intensity and pH environments within cell-free buffered reaction systems.

• Synthetic Building Block for Prostanoid Analogues  Supports organic synthetic laboratory work as a validated chemical scaffold, enabling derivative synthesis and structure-activity relationship exploration for innovative ophthalmic candidate molecules.

• Compatible Preparation of Ocular Cell Assay Buffers  Dissolves efficiently in organic co-solvents and can be mixed with physiological salt solutions to formulate multi-component working buffers for ocular cell pharmacology research.

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Application Fields

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• In-vitro Ocular Prostanoid Signaling Mechanism Exploration

Reference reagent to prepare cell culture working solutions for FP receptor screening, supporting iterative candidate discovery workflows in ophthalmic pharmacology.

• Pre-formulation Development of Ophthalmic Liquid Preparations

Applied in bench-scale development of eye drops and ophthalmic emulsions, acting as core active raw material to test innovative delivery strategies targeting ocular tissue.

• Pharmaceutical Analytical Validation and Impurity Characterization

High-purity reference standard for related-substance profiling, photostability comparison and validation of analytical detection methods for ophthalmic raw materials.

 

 

Business Scope

 

 

0421001

 

Packaging And Transportation Methods

 

 

001

 

Certificationss

 

 

222

 

FAQ

 

 

Q1: What research scenarios is Latanoprost Powder ≥99.0% suitable for?
A1: It is mainly applied for in-vitro FP prostaglandin receptor research, photodegradation kinetic analysis and preliminary feasibility evaluation of ophthalmic liquid formulations.
Q2:What is its CAS registry ID?
A2: CAS 130209-82-4.
Q3: Can packing weight and purity grade be adjusted?
A3: Yes, both net quantity and assay standard can be customized to match your laboratory experimental setup.
Q4: Can Latanoprost Powder be used for human clinical treatment?
A4: This material is limited solely to laboratory research purposes. It is not authorized for administration to humans or animals in clinical settings.
Q5: What storage measures should be taken for Latanoprost raw material?
A5: Keep in tightly sealed, light-blocking containers under dry ambient conditions. Avoid intense light exposure and high humidity to prevent chemical decomposition and moisture absorption.
Q6: How does solubility perform in water and organic solvents?
A6: Practically insoluble in purified water; freely soluble in ethanol, DMSO and chloroform; poorly dissolved in aliphatic nonpolar solvents.
Q7: Will inter-batch impurity differences interfere with cell receptor binding tests?
A7: Multi-stage low-temperature purification reduces impurity levels; each shipment comes with full impurity test reports for experimental risk evaluation. 
 
How To Cooperate With Us?

Our address

No. 56, Jinye 1st Road, Hi-Tech Zone, Xi'an,Shaanxi   Province, China

Phone Number

17792692163

E-mail

qinhe06@xaltbio.com

 

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