Tinidazole Powder

Tinidazole Powder
Details
Product Name: Tinidazole Powder
Alternative Names: 1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitroimidazole, nitroimidazole anti-infective lab raw powder
Specification: HPLC ≥99.0%, research grade, customized purity specifications available
CAS No.: 19387-91-8
Appearance: White to off-white crystalline powder. It exhibits limited solubility in pure water, dissolves readily in DMSO and has slight solubility in ethanol. Low moisture absorption capacity; stable under dry, ambient conditions.
Core Advantages: Multi-step recrystallization optimizes particle size distribution and reduces residual synthetic intermediates. Heavy metal and residual solvent testing follows pharmacopoeial research specifications. Inhibitory activity against anaerobes and protozoa remains consistent across batches. Complete mass spectrum identification and impurity profiling are supplied per lot. It can be mixed with microbial growth medium to support in-vitro susceptibility tests of anaerobic pathogens.
Service Support: Small laboratory trial lots are stocked for quick dispatch. Vacuum moisture-proof packaging protects crystalline powder during long-distance logistics. Multiple packing specifications can be customized. COA and HPLC chromatograms are provided together with goods. Our technical team offers support on medium preparation and dissolution method development for anti-infective preclinical research.
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Product Details

Product Description

 

Tinidazole falls within the nitroimidazole chemical family, designed for laboratory investigation of anaerobic microbe and protozoan growth suppression. Its characteristic nitroimidazole heterocyclic framework is widely used to prepare microbial incubation medium for establishing in-vitro pathogen infection models. Researchers adopt this raw powder to explore microbial DNA damage pathways triggered by nitro group reduction, build in-vitro models of anaerobic infectious diseases, carry out long-term hydrolytic stability tests, and assess its potential as an intermediate for oral anti-infective solid formulations.
When stored in sealed dry containers at room temperature, this high-purity powder maintains stable physicochemical features within pathogen test buffer matrices, serving as reliable reference substance for antibacterial susceptibility assays and hydrolytic degradation research. It is suitable for early-stage oral solid formulation screening and structural modification exploration of nitroheterocyclic compounds.

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COA

 

 

Items Specifications
Appearance Yellow powder
Loss on Drying ≤1.0%
Residue on Ignition ≥0.1%
Lead ≤2 ppm
Arsenic ≤1 ppm
Cadmium ≤1 ppm
Mercury ≤0.1 ppm
Total Aerobic Count ≤1000 CFU/g
Yeast & Mold ≤100 CFU/g
E.Coli, Salmonella Negative
Shelf Life 24 months (sealed and stored away from light)

 

Functions and Effects

 

 

•In-vitro Susceptibility Test for Anaerobic Microbes

Acts as test agent added into microbial incubation systems to assess inhibitory potency against diverse anaerobic bacteria and protozoa in anti-infective pharmacological screening.


•Hydrolysis Stability Study of Small Molecules

Serves as certified reference substance to track hydrolytic degradation byproduct formation under variable pH and thermal conditions inside cell-free buffered reaction systems.


•Chemical Scaffold for Nitroimidazole Derivative Synthesis Provides validated core chemical skeleton for organic chemistry labs to synthesize derivatives and explore structure-activity relationships for novel anti-infective lead compounds.


•Preparation of Buffered Microbial Incubation Medium 

Soluble in DMSO and diluted aqueous buffer systems. It can be blended with physiological salts to prepare multi-component working buffers for anti-infective cell and microbiology research.

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Application Fields

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•Mechanism Research of Anaerobic Anti-infective Pharmacology

Reference reagent for preparing microbial culture working solutions for pathogen susceptibility screening, supporting lead compound discovery workflows in anti-infective research.
•Pre-formulation Study of Oral Solid Preparations

Deployed in bench-scale development of tablets and capsules, acting as core active raw material to test innovative oral delivery strategies for anti-infective molecules.


•Analytical Method Validation and Impurity Identification for Anti-infective Raw Materials

High-purity reference standard for impurity profiling, stability comparison and analytical method verification of pharmaceutical anti-infective raw materials.

 

 

Business Scope

 

 

0421001

 

Packaging And Transportation Methods

 

 

001

 

Certificationss

 

 

222

 

FAQ

 

 

Q1:What research directions is Tinidazole Powder ≥99.0% mainly applied to?
A:It is used for in-vitro anaerobic bacteria and protozoan inhibition studies, small molecule hydrolytic stability analysis and preliminary oral solid formulation feasibility research.
Q2:What is its CAS registration number?
A:CAS 19387-91-8.
 
Q3:Can packing size and purity standard be modified?
A:Yes, net weight and assay grade can be adjusted according to your laboratory experimental requirements.
 
Q4:Can Tinidazole Powder be adopted for human clinical treatment?
A:This product is for laboratory research only. It cannot be applied for clinical therapy on humans or animals.
Q5:What storage requirements apply to Tinidazole raw powder?
A:Store in tightly sealed dry containers at ambient temperature. Avoid high humidity to prevent moisture uptake and crystal aggregation.
Q6:How does solubility behave in water and organic solvents?
A:Sparingly soluble in purified water; freely soluble in DMSO; slightly soluble in ethanol; poorly soluble in nonpolar organic solvents.
Q7:Will batch impurity differences affect microbial inhibition tests?
A:Multi-cycle recrystallization lowers impurity levels; each batch is accompanied by complete impurity test data for your experimental risk assessment.
Q8:Are small trial samples available for initial pharmacological screening?
A:Yes, sample packages from 100mg to 1g are offered for your preliminary in-vitro pharmacological evaluation.
 
How To Cooperate With Us?

Our address

No. 56, Jinye 1st Road, Hi-Tech Zone, Xi'an,Shaanxi   Province, China

Phone Number

18192393517

E-mail

dennis04@xaltbio.com

 

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