Tolterodine Tartrate Powder

Tolterodine Tartrate Powder
Details
Product Name: Tolterodine Tartrate Powder
Alternative Names: (R)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropan-1-amine L-tartrate, chiral antimuscarinic lab raw powder
Specification: HPLC ≥99.0%, research grade, customized purity available
CAS No.: 124937-52-6
Appearance: White, odourless crystalline powder. Moderate solubility in purified water under acidic conditions, soluble in methanol, slightly soluble in ethanol, insoluble in nonpolar solvents. Stable under dry, dim ambient storage.
Core Advantages: Chiral controlled recrystallization secures high single-enantiomer purity and uniform crystal morphology. Heavy metal and residual solvent tests comply with pharmaceutical research criteria. Muscarinic receptor antagonistic potency remains consistent across batches. Full chiral impurity detection and mass spectral identification are provided per lot. Compatible with bladder smooth muscle cell culture medium to support in-vitro urological receptor pharmacology tests.
Service Support: Small laboratory trial lots are stocked. Moisture-resistant sealed packaging protects chiral crystalline powder during cross-region shipment. Multiple packing sizes can be customized. COA, HPLC chromatogram and chiral analysis reports are attached to goods. Our technical team offers guidance on dissolution testing and solid-state research for urological preclinical formulations.
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Product Details

Product Description

 

Tolterodine Tartrate is a selective muscarinic receptor antagonist developed for laboratory research of bladder detrusor contraction signal regulation. Its distinctive chiral diaryl propylamine backbone is widely used to prepare smooth muscle cell incubation medium to build in-vitro bladder tissue models. Researchers adopt this raw powder to investigate binding affinity against M2/M3 muscarinic receptor subtypes, establish cell models of overactive bladder, conduct pH-dependent stability tests, and assess its potential as an intermediate for oral urological solid formulations.
When stored in sealed dry, dim-light containers at room temperature, this high-purity powder maintains stable physicochemical properties inside urological simulation buffer matrices, serving as reliable reference substance for receptor binding assays and pH-triggered degradation research. It fits early-stage oral solid formulation screening and structural modification exploration of antimuscarinic chiral molecules.

product-1292-1280

COA

 

 

Items Specifications
Appearance Yellow powder
Loss on Drying ≤1.0%
Residue on Ignition ≥0.1%
Lead ≤2 ppm
Arsenic ≤1 ppm
Cadmium ≤1 ppm
Mercury ≤0.1 ppm
Total Aerobic Count ≤1000 CFU/g
Yeast & Mold ≤100 CFU/g
E.Coli, Salmonella Negative
Shelf Life 24 months (sealed and stored away from light)

 

Functions and Effects

 

 

•In-vitro Muscarinic Receptor Competitive Binding Assay Acts as test agent inside cell incubation systems to evaluate antagonistic activity targeting muscarinic receptor subtypes during urological pharmacological screening.
•pH-dependent Degradation Kinetic Research

Serves as certified reference substance to track degradation byproduct formation under variable pH and thermal conditions within cell-free buffered reaction systems.


•Chemical Scaffold for Antimuscarinic Chiral Derivative Synthesis

Provides validated core chemical skeleton for organic chemistry labs to synthesize chiral derivatives and explore structure-activity relationships for novel urological lead compounds.
•Preparation of Buffered Bladder Smooth Muscle Cell Culture Medium

Soluble in methanol and weak acidic aqueous buffer systems. It can be blended with physiological salts to prepare multi-component working buffers for urological cell pharmacology research.

product-1279-1674

 

 

Application Fields

product-1497-1279

 

 

 

In-vitro Urological Muscarinic Signal Mechanism Research  Reference reagent for preparing smooth muscle cell working solutions for receptor screening, supporting lead compound discovery workflows in urological pharmacology.

Pre-formulation Study of Oral Solid Preparations 

Deployed in bench-scale development of tablets and capsules, acting as core active raw material to test innovative oral delivery strategies for bladder-targeted molecules.

Chiral Pharmaceutical Analytical Validation and Impurity Identification

 High-purity reference standard for chiral impurity profiling, pH stability comparison and analytical method verification for chiral pharmaceutical raw materials.

 

 

 

Business Scope

 

 

0421001

 

Packaging And Transportation Methods

 

 

001

 

Certificationss

 

 

222

 

FAQ

 

 

Q1:What research directions is Tolterodine Tartrate Powder ≥99.0% mainly applied to?
A:It is used for in-vitro muscarinic receptor antagonism research, chiral molecule pH-dependent stability analysis and preliminary oral solid formulation feasibility research.
Q2:What is its CAS registration number?
A:CAS 124937-52-6.
 
Q3:Can packing size and purity standard be modified?
A:Yes, net weight and assay grade can be adjusted according to your laboratory experimental requirements.
 
Q4:Can Tolterodine Tartrate Powder be adopted for human clinical treatment?
A:This product is for laboratory research only. It cannot be applied for clinical therapy on humans or animals.
Q5:What storage requirements apply to Tolterodine Tartrate raw powder?
A:Store in tightly sealed, light-blocking dry containers at ambient temperature. Avoid intense light and high humidity to prevent chemical decomposition and moisture uptake.
Q6:How does solubility behave in water and organic solvents?
A:Sparingly soluble in purified water under neutral conditions; freely soluble in methanol; slightly soluble in ethanol; practically insoluble in nonpolar organic solvents.
Q7:Will batch impurity differences affect muscarinic receptor binding tests?
A:Chiral controlled recrystallization lowers impurity levels; each batch is accompanied by complete chiral and impurity test data for your experimental risk assessment.
Q8:Are small trial samples available for initial pharmacological screening?
A:Yes, sample packages from 100mg to 1g are offered for your preliminary in-vitro pharmacological evaluation.
 
How To Cooperate With Us?

Our address

No. 56, Jinye 1st Road, Hi-Tech Zone, Xi'an,Shaanxi   Province, China

Phone Number

18192393517

E-mail

dennis04@xaltbio.com

 

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